Latest seminar series

The Past, Present and Future of Pediatric Drug Development

Downloading our Scientific Posters

You are about to download this document, please enter your contact details below to start downloading.

Scientific Posters

Development and optimization of MR formulations in the absence of predictive laboratory or preclinical models

The integration of formulation design space, real-time GMP manufacturing, and an iterative sequential pharmacokinetic (PK) study in healthy volunteers was successfully applied to develop an HPMC matrix tablet that achieved the desired PK characteristics for SLx-2101.The key formulation variables influencing performance were the range of dose and release rate, hence a two-dimensional (2D) design space was mapped by manufacturing and characterizing four “regulatory batches” bracketing the corners of the compositional ranges.

Would you like to receive further scientific content including case studies, whitepapers and seminar and webinar invitations?
You can find out how we handle your personal information in our privacy policy here.

Ask us a question