Translational Pharmaceutics
How do I accelerate my drug development?
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Translational Pharmaceutics®
Accelerate your drug development
Translational Pharmaceutics is significantly faster than traditional drug development, as proved in a recent Tufts CSDD White Paper. On average our customers save >12 months of development time. This translates into R&D cost savings of >$100 million as well as the benefit of getting products to market much sooner.
Unlike traditional drug development, Translational Pharmaceutics integrates a wide array of activities under a single service provider. This reduces the “white space” in development and shortens the times between clinical manufacturing and dosing, from months to days.
Simple or complex drug products are manufactured in real-time during the clinical study, with arising human data used to inform the composition of the next formulation to be manufactured and dosed.
Programs are led by a highly skilled cross-functional project manager and science team offering scientifically-rich decision-making to reduce the probability that a drug will fail in later stage clinical testing due to sub-optimal formulation performance.
Request a copy of our Translational Pharmaceutics white paper.
The Quotient Sciences Translational Pharmaceutics platform has been proven to reduce drug development timelines by over 12 months. Download a copy of the Tufts Center for the Study of Drug Development (CSDD) white paper benchmarking the Translational Pharmaceutics platform versus traditional drug development timelines.
Where is Translational Pharmaceutics used in drug development?
Translational Pharmaceutics is used to advance molecules across the full development cycle, with programs delivered via all routes of administration. Key applications within development process include:
- Transitioning molecules from first-in-human (FIH) to proof-of-concept (POC)
- Development and optimization of clinical formulations including enhanced solubility, modified release and pediatric dosage forms
- Life cycle management of late-stage and marketed products
- Evaluation of novel drug delivery technologies
Using our Translational Pharmaceutics approach, you can streamline your management of outsourced partners. Your program will be led by a single project manager who will manage an integrated cross-functional project team focused on delivering all of the components of traditional CDMO and CRO services — allowing you to capture multiple efficiencies.
The benefits of Translational Pharmaceutics
-
Reduces timelines
by 12 months or more
-
Delivers R&D cost savings
>$9.5 million per month of time saved
-
Conserves drug substance
by more than 85%
-
Real-time decision-making
based on emerging human clinical data
-
Provides flexibility
to adjust formulation composition within a study
-
Streamlines
vendor management
Overcome your drug delivery challenges
Dosage Forms
- Solids (tablets, capsules, multiparticulates)
- Non-sterile liquids (solutions and suspensions)
- Semi-solids (creams, oil, gels, ointments)
- Inhalation (DPI/MDI/nebulizers)
- Parenterals (solutions)
Routes of Delivery
- Oral
- Inhaled, pulmonary, nasal
- Topical
- Parenteral (subcutaneous, intravenous)
What customers are saying about Translational Pharmaceutics
"Our small biotech company worked with Quotient Sciences on developing a complex formulation and validating the different iterations of the formulation in PK clinical studies using the Translational Pharmaceutics approach. The project was successful, and we were generally impressed by the skillsets, professionalism, and courtesy of the company's scientists and other subject experts. We have also chosen to work with Quotient Sciences on two subsequent projects."
—Evecxia