Bioanalysis

Over 40 years of experience delivering rapid bioanalytical data in discovery, preclinical and clinical development stages.

Rapid bioanalytical data to meet your program's milestones

Our accredited facilities provide comprehensive bioanalytical support to studies at all stages of development.

We deliver rapid bioanalytical data in the discovery, preclinical, and clinical stages with advanced equipment and systems, including: LC-MS/MS, LC-HR-MS, ICP-MS, ICP-MS/MS, GC-MS, and GC-MS/MS.

We are experts in the development, validation, and application of bioanalytical assays with over 40 years of scientific expertise.

We have developed more than 400 methods (LC-MS, GC-MS, ICP-MS) for our customers, with expertise in areas such as insulin analogues & polypeptide drugs, elemental analysis, volatile drugs, and biomarkers.

We offer expert toxicokinetics (TK) and pharmacokinetics (PK) data analysis and reporting to support pre-clinical and clinical studies. Working together with our expert PK team, we can reduce the risk of downstream delays in later phases of your drug development.

Bioanalytical services for small molecule drug development

Our experts can quickly develop, validate, and implement bioanalytical LC-MS, GC-MS, and ICP-MS assays for small- and large-molecule drugs, biomarkers, and elements in compliance with regulatory standards.

Broad range of platforms

Liquid chromatography with mass spectrometry (LC-MS)
Inductively coupled plasma mass spectrometry (ICP-MS)
Gas chromatography with mass spectrometry (GC-MS)

High-resolution mass spectrometry

Liquid chromatography with ion-trap mass spectrometry (LC-TRAP-MS)
Liquid chromatography with time-of-flight mass spectrometry (LC-TOF-MS)

Global compliance and regulatory

Good Laboratory Practice (GLP)- and Good Clinical Practice (GCP)-accredited laboratories
US Food and Drug Administration (FDA)
European Medicines Agency (EMA)
UK Medicines and Healthcare products Regulatory Agency (MHRA)

Specialist areas of expertise

Insulin analogues and polypeptide drugs
Elemental analysis
Volatile drugs and biomarkers

Comprehensive bioanalytical support at every stage of your drug program

Our dedicated bioanalytical chemists are globally recognized and have decades of experience supporting all stages of drug development. Contact us today discuss your next program.

A closer look at our equipment and applications

Instrumentation	Applications
Inductively coupled plasma mass spectrometry (ICP-MS) Inductively coupled plasma tandem mass spectrometry (ICP-MS/MS)	Elemental analysis
Xevo ultra-performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS)	Analysis of small-molecule new chemical entities (NCEs) Analysis of peptides, small proteins, and new biological entities (NBEs) Highly sensitive, with a lower limit of quantification (LLOQ) <1 ng/mL High throughput
Quantum and Vantage UPLC-MS/MS	Analysis of small-molecule NCEs Sensitive, with a LLOQ ~1 ng/mL High throughput
Gas chromatography with mass spectrometry (GC-MS) Gas chromatography with tandem mass spectrometry (GC-MS/MS)	Detection and analysis of volatile analytes for NCEs and biomarkers
Liquid chromatography with quadrupole time-of-flight mass spectrometry (LC-QTOF-MS)	High-resolution structural identification for NCEs Peptide and protein identification NBE analysis
Liquid chromatography with inductively coupled plasma tandem mass spectrometry (LC-ICP-MS/MS)	Elemental speciation
Liquid chromatography with ion-trap mass spectrometry (LC-TRAP-MS)	High-resolution structural identification for NCEs