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Scientific Posters
Assessment of the Contribution of CYP2D6 to the Elimination of Idalopirdine as well as the Absolute Bioavailability Following Multiple Oral Dosing
This study assessed the contribution of CYP2D6 to the metabolization of idalopirdine by comparing pharmacokinetics in CYP2D6 extensive metabolizers (EM) and poor metabolizers (PM) following multiple oral dosing. Comparison of pharmacokinetic (PK) parameters in PMs and EMs may substitute for an interaction study of the effect of CYP2D6 inhibition
Scientific Posters
Applications of Lipid-based Formulations and the Benefits of Integrating Manufacturing and Clinical Testing in Formulation Selection
The purpose of this study is to analyze pharmaceutical and clinical data from multiple development programs to understand the drivers and outcomes of selecting and dosing different lipid formulations.
Scientific Posters
Why Archiving is a Crucial Part of Any Clinical Trial
A Quotient Sciences Poster by Erika Reategui, Director, GCP Quality Assurance, Quality Assurance: Why Archiving is a Crucial Part of Any Clinical Trial
Scientific Posters
A First-in-Human (FIH) Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses, and Alternative Formulations of R941552 (R552): A selective Receptor Interacting Protein 1 (RIP1) Kinase Inhibitor
Quotient Sciences Poster: A First-in-Human (FIH) Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses, and Alternative Formulations of R941552 (R552): A selective Receptor Interacting Protein 1 (RIP1) Kinase Inhibitor
Scientific Posters
An integrated radiolabelled study to determine the mass balance, metabolite profile and identification, and absolute bioavailability of nolasiban in healthy female subjects
Quotient Sciences Poster : An Integrated Radiolabelled Study to Determine the Mass Balance, Metabolite Profile and Identification and Absolute Bioavailability of Nolasiban in Healthy Female Subjects
Scientific Posters
Influence of drug loading and fillers on drug release from HPMC matrix tablets
Quotient Sciences' Poster: Influence of drug loading and fillers on drug release from HPMC matrix tablets
Scientific Posters
Development of modified release matrix tablet formulation using solid lipid Compritol 888 for a poorly water soluble drug
Quotient Sciences Poster: Development of modified release matrix tablet formulation using solid lipid Compritol 888 for a poorly water soluble drug
Scientific Posters
Analysis of Ranitidine Reference Materials Using a Six N-Nitrosamine LC-MS/MS Assay
Quotient Sciences EBF 2021 Poster: Analysis of Ranitidine Reference Materials Using a Six N-Nitrosamine LC-MS/MS Assay
Scientific Posters
EBF 2021- Novel Copper Protein Speciation Method for Calculating Serum Non Ceruloplasmin Copper: A Comparative Analysis
Download our poster from the EBF 2021 conference entitled: Novel Copper Protein Speciation Method for Calculating Serum Non Ceruloplasmin Copper: A Comparative Analysis
Scientific Posters
EBF 2021- Analysis of Ranitidine Reference Materials Using a Six N-Nitrosamine LC-MS/MS Assay
Download our poster from the EBF 2021 conference entitled: Analysis of Ranitidine Reference Materials Using a Six N-Nitrosamine LC-MS/MS Assay
Scientific Posters
Pharmaceutical and clinical performance comparisons of modified release multiparticulates and matrix tablet formulations
Access our latest poster from AAPS 2021- Pharmaceutical and clinical performance comparisons of modified release multiparticulates and matrix tablet formulations. The purpose of this study is to review practical experiences of head to head pharmaceutical and clinical comparisons of MUPs and matrix tablet platforms to identify an optimal MR formulation.
Scientific Posters
Development and Application of a PBPK Model Using Theoretical Particle Size Distribution to Describe in vivo D issolution to Predict the Impact of Formulation Changes on Oral Bioavailability of GB001
Download our AAPS 2021 poster entitled: Development and Application of a PBPK Model Using Theoretical Particle Size Distribution to Describe in vivo D issolution to Predict the Impact of Formulation Changes on Oral Bioavailability of GB001