Resource centre

Quotient scientists answer your questions surrounding spray drying, formulation optimization, GMP manufacturing and pediatric formulation.

A flexible, real-time adaptive GMP manufacturing model is required to support the increasing requirement for clinical trial conduct in small patient populations with challenging trial designs and treatment algorithms.

Pediatric formulation development is currently a hot topic within the pharmaceutical industry, this poster describes a feasibility study to assess the acceptability of solid dosage forms in children.

This poster explains the cocktail approach for assessing CYP450 drug-drug interaction liabilities including assessment of differential inhibition of liver and gut CYP3A4.

This poster describes a 2 part study combing an IV microtracer study with a conventional oral ADME study

The objective of this poster is to provide comparative information on the CTA and IND applications, highlighting factors that may influence companies in deciding where to conduct Phase I clinical research.

This poster describes how combining an intravenous (IV) microtracer regimen with an oral tracer regimen, can generate key pharmacokinetic (PK) parameters.

Formulation selection and development for ME-401, an oral, potent and selective inhibitor of phosphatidylinositol 3-kinase P110δ during a first-in-human study in healthy volunteers.

Development of novel radiolabelling method for low dose drug products for investigation of in Vivo performance in gamma scintigraphic studies.

A rapid in vitro screen method for assessing the potential for precipitation of solubilised drugs in the small intestine.

Working with Short Shelf-Life Products in Clinical Development – Driving Efficiencies and Overcoming Challenges

There has been increasing interest in the oral administration of antibodies for localised treatment of infections or other conditions in the gastrointestinal (GI) tract.