AAPS 2020 Poster: Scale-up Challenge of a Low-Dose Tablet Formulation through Blending and Roller Compaction Optimization

Download our scientific poster from AAPS 2020 entitled, 'Scale-up Challenge of a Low-Dose Tablet Formulation through Blending and Roller Compaction Optimization.' 

The purpose of this investigation was to address the content uniformity challenge faced during the scale-up for a low-dose tablet formulation of Drug X on an accelerated development program. Experiments were performed to demonstrate optimized processing before clinical trial manufacturing (CTM).