How to Optimize CMC and Clinical Strategies for Injectable & Oral Peptide Drugs

The exquisite specificity/selectivity, potency, and low toxicity of peptides make them attractive drug candidates. However, their rapid clearance, poor permeability, and potential instability (e.g., in solution and physiological environments) can make them challenging to develop. 

But recent advances in drug discovery and peptide engineering have led to significant progress in overcoming such challenges.