Peer Reviewed Publication , Clinical Pharmacology

A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics

23 January 2020

Oral itraconazole has variable pharmacokinetics and risks of adverse events associated with high plasma exposure. An inhalation formulation of itraconazole (PUR1900) is being developed to treat allergic bronchopulmonary 
aspergillosis, an allergic inflammatory disease occurring in asthmatics and patients with cystic fibrosis.

23 January 2020