Candidate Development
Selecting the right molecules for development
Knowing what it takes to develop a successful drug, we help clients select the best molecules for development.
Our unique integration of scientific capabilities enables us to provide a complete assessment of molecule “developability”. Through this, we quickly identify the best drug candidates – the potential winners – mitigating risks for our clients and shortening the time to reach the clinic.
Resources
Read our related case studies
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Info SheetDrug Substance Synthesis and ManufacturingTactical deployment of best-in-class synthesis technologies to minimize chemistry costs and move your drug substance supply off the critical path.
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Case StudiesDCS classification of NCE - Case studyUS Biotech wanted to determine the DCS (Developability Classification System) designation for their small molecule. This included project scope and outcomes of the project.
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Scientific PostersAAPS 2019 Poster- Comparison of Two In-Silico Modeling Programs, ADMET Predictor® and Percepta® to Predict Intrinsic Solubility and pKa of Poorly Soluble DrugsPresented at AAPS 2019: Aqueous solubility is a prerequisite for oral absorption of a drug and the pH-dependence of aqueous solubility is critical information to guide formulation development strategies. The purpose of this study was to evaluate the physical property modules in two commercially available in-silico modelling programs in predicting the pH solubility profiles as described by the ionization constant (pKa) and the intrinsic solubility of the unionized form.
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WebinarUpcoming Webinar: Strategies for Achieving Regulatory Milestones FasterSave your spot for our next webinar featuring a customer case study from Ensysce Biosciences on April 19, 2023. Dr. Vanessa Zann, Senior Drug Development Consultant, will be joined by Lynn Kirkpatrick, CEO of Ensysce Biosciences for this special presentation.
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