Articles & Publications , Formulation Development

Open-Label Study Assessing Relative and Absolute Bioavailability of Oral Camizestrant Formulations and Food Effects in Healthy Postmenopausal Women

21 January 2026
Overview

This study involving John McDermott (VP of Scientific Consulting) and Chris Roe (Principal Research Fellow, Scientific Consulting) at Quotient Sciences, investigates the impact of manufacturing changes during pivotal Phase 3 studies. 

This open-label, randomized crossover study of 32 postmenopausal healthy volunteers determined the relative bioavailability of a tablet used in early clinical studies.

The study was conducted by Quotient Sciences (Quotient) on behalf of AstraZeneca at a research site in Nottingham, UK

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Date
21 January 2026
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John McDermott

VP, Scientific Consulting

John McDermott leads Quotient Sciences' global drug development consulting, research fellows, modeling & simulation, and clien...

About John
Chris Roe

Principal Research Fellow

Chris Roe brings over 25 years’ experience across biopharmaceutics, clinical pharmacology and pharmaceutical sciences and applying...

About Chris
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