Isotope Labelling
Secure & rapid delivery of isotopically labelled (14C/SIL) materials for non-clinical & clinical human studies.
With over 30 years of successful delivery on-site, Quotient Sciences' highly trained chemists have extensive chemical and radiochemical knowledge and the experience required to supply consultancy and advice on the most suitable labelling positions for a variety of molecular entities.
Isotope Labelling Services Include:
•GMP & non GMP synthesis
•14C radiolabelling
•Ability to handle highly potent/high hazard compounds (cytotoxics)
•Synthesis of metabolites & reference standards aiding bioanalytical and metabolism studies
•Degradants and process impurities to support API development
•Route development and precursor synthesis for labelling with 3H and short-lived isotopes 11C and 18F
•Classical and non-classical synthetic techniques
•Flow chemistry
•Automated peptide synthesis capability
•Microbiological and bio-catalysis
•Stable isotope label (SIL) synthesis, including 2H, 13C, 15N & 18O
Isotope Labelling Resources
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Info SheetIsotope LabellingWhether you need isotopically labelled (14C/SIL) compounds for nonclinical or clinical metabolism studies and the quantification of materials in biological matrices, our expertise provides the necessary labelled materials tailored to support your studies.
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Case StudiesStable Isotope Labelling Case StudyMultiple, biotechnology and large-pharma companies needing isotope labelling support for their ADME/hAME studies
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Info SheetQuotient Sciences Corporate Brochure 2021Quotient Sciences is a drug development and manufacturing accelerator providing integrated programs and tailored services across the entire development pathway. Our corporate brochure provides a key summary of who we are, what we represent, our services and our marketplace differentiation.
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Case StudiesStability CapabilitiesDesignated team of highly experienced personnel who control all aspects of sample management and liaise closely with clients throughout the lifecycle of stability studies. Our aim is to provide robust, sound data on which shelf life and expiration dates for drug substance and drug products can be based. Whatever the phase of development our team can offer support. We also offer a stability protocol creation service if clients prefer not to supply stability protocols themselves. Robust systems are in place to ensure complete tracking of samples from receipt, through stability storage and time-point testing (or shipment if required), to study end.
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