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Clinical Pharmacology, First-in-Human

Accelerating First-in-Human (FIH) Trials to Proof of Concept (POC)

14 October 2025 Download

71 - 80 of 216 results

Scientific Posters, First-in-Human, Translational Pharmaceutics, Clinical Trial Manufacturing, Formulation Development
A First-in-Human (FIH) Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses, and Alternative Formulations of R941552 (R552): A selective Receptor Interacting Protein 1 (RIP1) Kinase Inhibitor
24 March 2022
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Articles & Publications, Drug Product Optimization
A Phase 1 Pharmacokinetic Drug Interaction Study of Belumosudil Coadministered With CYP3A4 Inhibitors and Inducers and Proton Pump Inhibitors
15 March 2022
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Articles & Publications, Drug Product Optimization
Absolute Bioavailability, Mass Balance, and Metabolic Profiling Assessment of [14C]-Belumosudil in Healthy Men: A Phase 1, Open-Label, 2-Part Study
15 March 2022
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Articles & Publications, Drug Product Optimization
ACCP: A Phase 1 Pharmacokinetic Drug Interaction Study of Belumosudil Coadministered With CYP3A4 Inhibitors and Inducers and Proton Pump Inhibitors
7 March 2022
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Articles & Publications, Human ADME, Clinical Pharmacology, First-in-Human
Astrazeneca - Characterization of Clinical ADME & Pharmacokinetics of Velsecorat Using an IV Microtracer Combined with an Inhaled Dose in Healthy Subjects
2 February 2022
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Articles & Publications, Modified Release, Formulation Development
Development of a Once‑Daily Modified‑Release Formulation for the Short Half‑Life RIPK1 Inhibitor GSK2982772 using DiffCORE Technology
10 January 2022
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Articles & Publications, Clinical Pharmacology
Effect of Miricorilant, a Selective Glucocorticoid Receptor Modulator, on Olanzapine-Associated Weight Gain in Healthy Subjects
3 January 2022
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Scientific Posters, First-in-Human
An integrated radiolabelled study to determine the mass balance, metabolite profile and identification, and absolute bioavailability of nolasiban in healthy female subjects
22 December 2021
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Scientific Posters, Formulation Development
Influence of drug loading and fillers on drug release from HPMC matrix tablets
22 December 2021
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Scientific Posters, Modified Release, Formulation Development
Development of modified release matrix tablet formulation using solid lipid Compritol 888 for a poorly water soluble drug
22 December 2021
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