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Clinical Pharmacology, First-in-Human, Proof-of-Concept, Patient Trials

First-in-Human Trials to Proof of Concept Info Sheet

14 October 2025 Download

71 - 80 of 221 results

Articles & Publications, Clinical Pharmacology
CC-99677: A Novel, Oral, Selective Covalent MK2 Inhibitor, Sustainably Reduces Pro-inflammatory Cytokine Production
23 August 2022
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Articles & Publications, Human ADME
ADME of opicapone in human healthy volunteers
16 June 2022
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On-Demand Webinars, Translational Pharmaceutics
Getting it Right Early: The Importance of Biopharmaceutics in Early Drug Development
1 June 2022
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Scientific Posters, Translational Pharmaceutics, Clinical Trial Manufacturing, First-in-Human
Why Archiving is a Crucial Part of Any Clinical Trial
17 May 2022
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Articles & Publications, Translational Pharmaceutics, Clinical Pharmacology, First-in-Human
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial
3 May 2022
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Scientific Posters, First-in-Human, Translational Pharmaceutics, Clinical Trial Manufacturing, Formulation Development
A First-in-Human (FIH) Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses, and Alternative Formulations of R941552 (R552): A selective Receptor Interacting Protein 1 (RIP1) Kinase Inhibitor
24 March 2022
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Articles & Publications, Drug Product Optimization
A Phase 1 Pharmacokinetic Drug Interaction Study of Belumosudil Coadministered With CYP3A4 Inhibitors and Inducers and Proton Pump Inhibitors
15 March 2022
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Articles & Publications, Drug Product Optimization
Absolute Bioavailability, Mass Balance, and Metabolic Profiling Assessment of [14C]-Belumosudil in Healthy Men: A Phase 1, Open-Label, 2-Part Study
15 March 2022
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Articles & Publications, Drug Product Optimization
ACCP: A Phase 1 Pharmacokinetic Drug Interaction Study of Belumosudil Coadministered With CYP3A4 Inhibitors and Inducers and Proton Pump Inhibitors
7 March 2022
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Articles & Publications, Human ADME, Clinical Pharmacology, First-in-Human
Astrazeneca - Characterization of Clinical ADME & Pharmacokinetics of Velsecorat Using an IV Microtracer Combined with an Inhaled Dose in Healthy Subjects
2 February 2022
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