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Clinical Pharmacology, First-in-Human, Proof-of-Concept, Patient Trials

First-in-Human Trials to Proof of Concept Info Sheet

14 October 2025 Download

1 - 7 of 7 results

Scientific Posters, Modelling & Simulation
A PBPK based simulation study to predict potential gastric transit time and permeability driven drug-drug interactions caused by Rybelsus®
18 December 2025
Scientific Posters, Modelling & Simulation, Sodium Salcaprozate SNAC, Oral Peptides, Peptide Drug Development, Pharmacokinetics
Physiologically Based Biopharmaceutics Modelling of the Effect of a Permeability Enhancer on the Absorption of a Highly Soluble and Poorly Permeable Small Peptide in Humans
6 November 2024
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Scientific Posters, Pediatrics, Clinical Pharmacology, Modelling & Simulation
ACoP 2022 Poster: Benznidazole pharmacokinetics in adults and children: Application of PBPK modelling
13 December 2022
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Scientific Posters, Modelling & Simulation, Clinical Pharmacology, Translational Pharmaceutics
Qualification of Gastroplus® PBPK modelling software to support decision-making in clinical development
13 December 2022
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Scientific Posters, Translational Pharmaceutics, Human ADME, Spray Drying, First-in-Human, Modelling & Simulation
AAPS 2019 Poster: Comparison of Two In-Silico Modeling Programs, ADMET Predictor® and Percepta® to Predict Intrinsic Solubility and pKa of Poorly Soluble Drugs
4 November 2019
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Scientific Posters, Solubility Enhancement, Modified Release, Modelling & Simulation
AAPS 2021: Development and Application of a PBPK Model Using Theoretical Particle Size Distribution to Describe in vivo D issolution to Predict the Impact of Formulation Changes on Oral Bioavailability of GB001
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Info Sheets, Clinical Pharmacology, Modelling & Simulation
PBPK Modeling & Simulation
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