Determining drug exposure is vital for the assessment of drug safety and efficacy. Quotient's Bioanalytical team, develop and refine methods so exposure can be assessed reliably and accurately in a variety of biological matrices.
Drug Substance Synthesis and Manufacturing
Tactical deployment of best-in-class synthesis technologies to minimize chemistry costs and move your drug substance supply off the critical path.
Thermal Rearrangement – Flow Chemistry - Case Study
Quotient Sciences seeking to improve the yield and purity of a US Biotech API intermediate using flow chemistry
API Development Case Study
Rapid development of a scalable route towards an analogue of a new drug substance, with definition of an optimal salt form for formulation
Biochemical Assay Optimization, Validation & Application Case Study
UK specialty-pharma company in need of biochemical assay for their regulatory non-clinical safety study
Stable Isotope Labelling Case Study
Multiple, biotechnology and large-pharma companies needing isotope labelling support for their ADME/hAME studies
Radiosynthesis via chemically unstable intermediate Case Study
US biopharmaceutical company seeking to improve stability of their chemically unstable API intermediate for radiochemical trials
Analytical and Microbiological support Case Study
UK Clinical Research Unit (CRU), developing intravenous (IV) products in need of analytical & microbiological support
Analysis of Insulin Analogues Case Study
European biotech company developing an NCE to fulfil an unmet patient need, required insulin analogue analysis to gain regulatory approval
Drug Substance Salt Selection Case Study
US Biopharmaceutical seeking drug substanceand salt screen selection for their molecule.
Global Clinical Trial Supplies
Quotient can ease the headache of global product supply logistics and accelerate your proof-of-concept timeline. We’ll develop and manufacture your drug product, and then seamlessly integrate into a flexible packaging, labelling & distribution strategy, tailored to your clinical trial.