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Scientific Posters

Pharmaceutical and clinical performance comparisons of modified release multiparticulates and matrix tablet formulations

Access our latest poster from AAPS 2021- Pharmaceutical and clinical performance comparisons of modified release multiparticulates and matrix tablet formulations. The purpose of this study is to review practical experiences of head to head pharmaceutical and clinical comparisons of MUPs and matrix tablet platforms to identify an optimal MR formulation.

Scientific Posters

Development and Application of a PBPK Model Using Theoretical Particle Size Distribution to Describe in vivo D issolution to Predict the Impact of Formulation Changes on Oral Bioavailability of GB001

Download our AAPS 2021 poster entitled: Development and Application of a PBPK Model Using Theoretical Particle Size Distribution to Describe in vivo D issolution to Predict the Impact of Formulation Changes on Oral Bioavailability of GB001

Scientific Posters

EuPFI 2021 - Taste Assessment Study of Belumosudil to Inform an Integrated Paediatric Formulation Development Program

Presented at the annual EuPFI event, this poster documents the project of Belumosudil, a ROCK2 selective inhibitor, is currently in development for the treatment of immune disorders.

Scientific Posters

EuPFI 2021-Development of a Novel Paediatric Belumosudil Oral Suspension

Download our EuPFI 2021 Conference Poster entitled: Development of a Novel Paediatric Belumosudil Oral Suspension

Scientific Posters

ISSX NA 2021 - An Integrated Radiolabelled Study to Determine the Mass Balance, Metabolite Profile and Identification and absolute bioavailability of Nolasiban in Healthy Female Subjects

Presented at the 24th North American ISSX Meeting, in this poster, we determine Mass Balance, Metabolite Profile and Identification and Absolute Bioavailability of Nolasiban in Healthy Female Subjects, via an integrated radiolabelled study.

Integrated Programs: Early Development

Simplify early development and accelerate to Proof-of Concept Proof-of-Concept (POC) is a key milestone in the development of a new drug candidate. At Quotient Sciences, we understand the increasing pressures on R&D budgets, therefore the need to transition molecules through early development to POC needs to be fast and cost-effective.

Peer Reviewed Publication

Scientific Paper_Pharmacokinetics and Metabolism of Ziritaxestat (GLPG1690) in Healthy Male Volunteers Following Intravenous and Oral Administration

Download our scientific paper entitled: Pharmacokinetics and Metabolism of Ziritaxestat (GLPG1690) in Healthy Male Volunteers Following Intravenous and Oral Administration

Scientific Posters

CRS 2021 Poster-Using formulation design spaces and clinical data to optimize development of modified release (MR) dosage forms

Download our CRS 2021 conference poster entitled: Using formulation design spaces and clinical data to optimize development of modified release (MR) dosage forms

Quotient Sciences Corporate Brochure 2022

Quotient Sciences is a drug development and manufacturing accelerator providing integrated programs and tailored services across the entire development pathway. Our corporate brochure provides a key summary of who we are, what we represent, our services and our marketplace differentiation.

Stability Capabilities

Designated team of highly experienced personnel who control all aspects of sample management and liaise closely with clients throughout the lifecycle of stability studies. Our aim is to provide robust, sound data on which shelf life and expiration dates for drug substance and drug products can be based. Whatever the phase of development our team can offer support. We also offer a stability protocol creation service if clients prefer not to supply stability protocols themselves. Robust systems are in place to ensure complete tracking of samples from receipt, through stability storage and time-point testing (or shipment if required), to study end.

Microbiology Services

Quotient Sciences' extensive experience permits testing of difficult products that have not previously been analyzed. We are specialists at the microbial analysis of radiolabelled compounds and are able to handle cytotoxic, high potency compounds and controlled substances. Our flexible approach allows us to offer both on-site microbiological testing and analysis of products made off-site.

Isotope Labelling

Whether you need isotopically labelled (14C/SIL) compounds for nonclinical or clinical metabolism studies and the quantification of materials in biological matrices, our expertise provides the necessary labelled materials tailored to support your studies.