Quotient Sciences’ Translational Pharmaceutics® platform innovates the way you design and implement your drug development program. It offers you integrated formulation development, real-time adaptive GMP manufacturing and clinical research capabilities proven to reduce drug development costs and shorten timelines.
Translational Pharmaceutics transforms the traditional approach of outsourcing development work to separate contract development and manufacturing organizations (CDMOs) and contract research organizations (CROs) – simplifying and streamlining your outsourcing and program management.
Our team works with you to design a customized solution to accelerate both your simple and complex early drug development programs.
We offer expert medical and scientific assessment of your objectives and interpretation of your data. Quotient supports you with flexible, adaptive solutions addressing critical steps in your drug development process:
How do I accelerate my molecule to Proof-of-Concept?
How do I optimize and validate my formulation?
How can I simplify the delivery of my human ADME study?
The benefits of Translational Pharmaceutics
When you need to quickly identify your opportunity and design the best quality solution, Quotient is your answer.
Reduces timelines
by six months or more
Delivers cost savings
in excess of $500,000
Conserves drug substance
by more than 85%
Real-time decision-making
Facilitates real-time decision making based on emerging human clinical data
Provides flexibility
to adjust formulation composition within a study
Streamlines
vendor management
Reduce time with Translational Pharmaceutics
Results have proved that you can gain up to 6 months from lab to clinic comparing to a conventional approach.
9-12
months
Conventional approach
3-4
months
Quotient Sciences' approach
1
Formulation & process development
Formulation & process development
2
Transfer to GMP
IMPD submission
3
Process development & verification
CT manufacture & release
4
Stability study
Dosing
5
IMPD Submission
6
CT manufacture & release
7
Ship to clinical site
8
Dosing
Overcome your drug delivery challenges
With Translational Pharmaceutics, our scientists help you overcome the drug delivery challenges presented by your molecule for all dosage forms and routes of delivery.
Dosage Forms
Solids (tablets, capsules, multiparticulates)
Non-sterile liquids (solutions and suspensions)
Semi-solids (creams, oil, gels, ointments)
Inhalation (DPI/MDI/nebulizers)
Parenterals (solutions).
Routes of Delivery
Oral
Inhaled, pulmonary, nasal
Topical
Parenteral (subcutaneous, intravenous)
Using our Translational Pharmaceutics approach, you can streamline your management of outsourced partners. Your program will be led by a single project manager who will manage an integrated cross-functional project team focused on delivering all of the components of traditional CDMO and CRO services — allowing you to capture multiple efficiencies.
Which applications could help me?
When you need to quickly identify your opportunity and design the best quality solution, Quotient is your answer.
“The company’s ability to integrate manufacturing and dosing really accelerated the conduct of the study and was one of the main reasons that Corcept selected Quotient to undertake the study.”
“After taking everything into account — the manufacturing costs of a traditional CMO model, creating multiple lots of material that may never get used, etc. — the Translational Pharmaceutics approach was a cost-effective option, especially when we took the additional cost of time saved into consideration.”
“Having an integrated way of working is truly innovative and offers a company like Clovis a really efficient option. The entire study was a very positive experience.”
“The understanding we have gained through working with Quotient — in terms of both the formulation development and the manufacturing — will be invaluable.”
