Taste masking for oral dosage forms is a crucial aspect of formulation development.
Nazim Kanji, Executive Director of Pediatric Services at Quotient Sciences, comments on taste masking strategies in a recent article with PharmTech.
Thoughtful design and development of drug products are vital for ensuring patient acceptability and compliance, which ultimately contribute to achieving the desired clinical outcomes. In a recent article with PharmTech, Nazim Kanji, Executive Director of Pediatric Services at Quotient Sciences, comments on taste masking strategies that drug developers and their CRDMO partners should keep in mind.
Numerous active pharmaceutical ingredients (APIs) have a bitter taste, texture, or undesirable qualities that make it a challenge to create palatable medications. “Undesirable taste is a common issue in medicines across all therapeutic areas, from antibiotics and painkillers to antihistamines and decongestants,” he notes. He discusses reverse-enteric polymers, one strategy being used for taste masking due to their pH-dependent solubility, among other factors that should be considered.
Read the full article, Evolving Approaches to Taste Masking, at the PharmTech website.
