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Corporate Overview Info Sheet

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Info Sheets , Translational Pharmaceutics , Clinical Pharmacology , Drug Product

Corporate Overview Info Sheet

10 March 2025
Overview

Integrated services and trusted scientific insight brought to every molecule and program.

Learn more about the benefits of working with us at Quotient Sciences, our state-of-the-art global facilities in both the US and UK, and our core services, including drug product development & manufacturing, Translational Pharmaceutics®, and clinical pharmacology. 

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Date
10 March 2025

Drug Product Development & Manufacturing Services Info Sheet

Drug manufacturing - women holding a pill
Info Sheets , Drug Product , Info Sheet

Drug Product Development & Manufacturing Services Info Sheet

10 March 2025
Overview

Achieve your molecule’s next milestone with fit-for-phase drug product formulations

Backed by trusted data and the expertise you need to navigate the increasing complexity of small molecule and synthetic peptide therapeutics, our adaptive approach assures scalable solutions for your molecule’s development—from preclinical through commercial drug product formulation, manufacturing, and supply. 

Learn more about our drug product capabilities in our info sheet.

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Date
10 March 2025

Thierry Van Nieuwenhove comments on the future of Pharma Manufacturing

Articles & Publications , Thierry Van Nieuwenhove

Thierry Van Nieuwenhove comments on the future of Pharma Manufacturing

Hexagons on blue gradient background with Quotient Sciences logo

In this article by Manufacturing Chemist, Thierry Van Nieuwenhove, CEO of Quotient Sciences, discusses the future of pharma manufacturing.

Ahead of the upcoming DCAT, Dr. Kevin Robinson caught up with pharmaceutical industry experts to discuss how they’re innovating for resilience and sustainability in 2025 and beyond.

Thierry Van Nieuwenhove, CEO of Quotient Sciences recognizes that sustainability and resilience are critical to the future of pharmaceutical development supply chains.

Continue reading the full article on Manufacturing Chemist.

 

First-in-human safety, tolerability, pharmacokinetics and pilot food-effect study of the candidate antimalarial compound MMV367

Articles & Publications , First-in-Human , Clinical Pharmacology

First-in-human safety, tolerability, pharmacokinetics and pilot food-effect study of the candidate antimalarial compound MMV367

12 March 2024
Overview

This first-in-human study enrolled 47 healthy male and female participants. Part 1 was a randomised, double-blind, placebo-controlled study in which four sequential fasted cohorts received MMV367 single ascending doses (100, 300, 750 and 1500 mg) orplacebo (six active, two placebo per cohort). 

Part 2 was a randomised, open-label crossover (fed-fasted) pilot food-effect study of MMV367 440 mg (n = 8). 

In Part 3 MMV367 400 mg was administered once daily for 3 days in a single cohort (six active, two placebo).

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Date
12 March 2024

Dr. Dolly Jacob - Director, Integrated Development Services

Dolly Jacob

Dr. Dolly Jacob

Director, Integrated Development Services

Subject Expert
About

Dr. Dolly Jacob has over 20 years’ experience in the pharmaceutical industry, spanning from preclinical formulation development, through early clinical formulation development into late-stage product development. In her role as Director, Integrated Development Services, Early Development she is responsible for providing scientific and technical support to business development team for early drug product development strategies and implementation. Since joining Quotient Sciences in 2015, Dolly has led and supported development teams and global Translational Pharmaceutics programs.

Dolly has an interest in enabling technologies for bioavailability enhancement and innovative strategies to develop formulations for challenging molecules and clinical indications.

Previously Dolly has worked for 3M Healthcare, Astra Zeneca and Cipla Ltd. Dolly’s experience and expertise spans a wide range of dosage forms and drug delivery systems, including oral products, modified release, sterile parenteral, topical and solubility enhancing technologies.

Dolly holds a PhD in Pharmaceutical Sciences from De Montfort University, UK and Bachelor and Master Pharmacy degrees from Universities in India. 

Pharmacokinetics, Pharmacodynamics and Bioavailability of ACM-001.1 (S-Pindolol Benzoate) in Healthy Volunteers

Articles & Publications , Pharmacokinetics , Pharmacodynamics

Pharmacokinetics, Pharmacodynamics and Bioavailability of ACM-001.1 (S-Pindolol Benzoate) in Healthy Volunteers

13 December 2023
Overview

A Phase 2a clinical trial demonstrated that S-pindolol can reverse weight loss and improve fat-free mass in patients with cancer-related weight loss. 

A comparative phase I bioavailability study of S-pindolol and racemic pindolol was performed to support the development of S-pindolol in cancer cachexia.

This two-part study assessed the comparative bioavailability and pharmacokinetics of single doses of S-pindolol benzoate (ACM-001.1) or pindolol (Part 1) and the steady-state pharmacokinetics and pharmacodynamics of multiple doses of ACM001.1 and pindolol (Part 2) in healthy volunteers (NCT06028321). ACM-001.1 5, 10 and 15mg and pindolol 15, 20 and 30mg were 
tested. 

 

 

 

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Date
13 December 2023

Quotient Sciences Recognized as a Winner of 2025 CDMO Leadership Awards

Awards & Recognition

Quotient Sciences Recognized as a Winner of 2025 CDMO Leadership Awards

Quotient Sciences Wins 2025 CDMO Leadership Awards

Quotient Sciences has been recognized as a 2025 CDMO Leadership Awards winner in the category of Small Molecule Dosage Form – Global. The company is also a finalist for a champion award in the same category, with the award ceremony presented in March. The CDMO Leadership Awards recognize the best contract development and manufacturing organizations (CDMOs) across global and regional categories, with some changes implemented for 2025. 

“For the 14th annual Outsourced Pharma CDMO Leadership Awards, we’ve added innovation to the way we select award winners, and excitement to how we will reveal those winners. The innovation comes with new award categories and enhanced scoring methodology.” said Louis Garguilo, Chief Editor, Outsourced Pharma, about the changes to this year’s awards. 

More than 210 CDMOs were evaluated by customers from global pharma and biotech companies based on their work with providers on an outsourced project within the past 24 months. Sponsors provide their ratings of contract development and manufacturing organizations based on their recent projects, and feedback is reviewed to determine leading CDMOs in each category. New for 2025 are categories based on outsourcing need, in the areas of: Biologics, Cell & Gene Therapy, Small Molecule API, and Small Molecule Dosage Form.

“We are thrilled to introduce our 2025 CDMO Leadership Awards finalists to the Outsourcing community, and honored to offer such an important tool for drug sponsors in selecting their best-fit partner to help bring life-saving therapies to market,” said Outsourced Pharma Chief Editor Louis Garguilo. “The new categories and enhanced scoring methodology that went into this year’s appraisal bring an improved experience for drug sponsors using the resource as well as an ever-so-coveted distinction for the CDMOs. The unveiling of the award champions during our celebration in March will be an exciting new addition to the festivities.” 

See the full list of nominees and winners presented by Outsourced Pharma and Life Science Leader

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